➤ Understanding Regenerative Medicine

What Is Regenerative Medicine?

Regenerative medicine is a branch of medicine that aims to repair or replace damaged cells, tissues and organs, using the body’s own healing processes, living cells and biological products. Instead of only managing symptoms, it works to support the body’s ability to heal itself.

Treatments range from stem cell therapy and exosomes to platelet-rich plasma (PRP) and cell-based immunotherapy. At IRM Hospital, Institute of Regenerative Medicine, every regenerative treatment is offered only after a specialist assessment, and many cell products are prepared in our own laboratory, Regen Cell Bio.

Two Sources of Cells

Autologous: cells or blood taken from your own body, such as bone marrow, fat tissue or the plasma used in PRP.

Allogeneic: cells from a carefully screened donor source, such as umbilical cord tissue (Wharton’s jelly), placenta or amniotic fluid.

Your specialist explains which source suits your condition.

➤ How It Works

How Regenerative Treatments Support Healing

Regenerative therapies deliver living cells, or the signals they produce, to an injured or diseased area. These can help calm inflammation, support tissue repair and encourage the body’s own cells to work better.

Results differ from person to person, so every treatment plan at IRM starts with a full specialist assessment.

➤ Our Therapies

Regenerative Therapies at IRM Hospital

IRM Hospital offers a full range of regenerative treatments under one roof. Your specialist recommends a therapy only after reviewing your condition, medical history and test results.

Core Regenerative Therapies

Our main regenerative treatments. Stem cells, exosomes and immune cells are prepared in our own laboratory, and PRP is made from your own blood.

Infusion & Wellness Therapies

Treatments given through a drip or injection to support the body’s overall health and recovery, always after a medical review.

IV Therapy (Glutathione, Vitamin C, NAD+)

Vitamins, antioxidants and coenzymes delivered directly into the bloodstream through a drip, so they do not pass through the digestive system. Glutathione and vitamin C are antioxidants; NAD+ is a coenzyme found in every cell and involved in energy production.

Considered for: nutritional and antioxidant support, wellness and recovery, after a medical review.

Peptide Therapy

Peptides are short chains of amino acids that act as signalling molecules in the body, and natural levels can fall with age. Specific peptides are chosen for a defined goal and used under medical supervision.

Considered for: recovery, wellness and age-related concerns, depending on the peptide chosen.

EBO2 (Blood Oxygenation & Ozonation)

EBO2 stands for Extracorporeal Blood Oxygenation and Ozonation. In a procedure similar to dialysis, blood is circulated outside the body through a filter, treated with medical ozone and oxygen, and returned to the body.

Considered for: selected patients after specialist assessment. Scientific evidence for EBO2 is still developing.

Skin, Gene & Advanced Science

Cultured skin and hair cells for repair and rejuvenation, plus gene therapy and 3D bioprinting, fields where science is moving fast and every case is assessed individually.

Cultured Fibroblasts, Keratinocytes & Hair Follicle Cells

Skin and hair cells grown in our lab. Fibroblasts produce collagen and elastin that keep skin firm; keratinocytes form the skin’s outer layer and help wounds close; hair follicle cells are linked to hair growth.

Considered for: wrinkles and loose skin, scars, burns, wound healing and hair loss.

Gene Therapy

Gene therapy treats disease by replacing a faulty gene, switching off a gene that is not working properly, or adding a new gene. It is a specialised and fast-developing field.

Considered for: selected inherited and acquired conditions. Our specialists assess whether a gene-based approach, including clinical research options, may be appropriate.

3D Bioprinting (Research & Laboratory Science)

3D bioprinting builds living tissue structures layer by layer, using cells and other biocompatible materials as “bio-inks”. Today it is used mainly in research, tissue engineering and drug testing.

Considered for: laboratory and research work. Clinical uses such as printed skin and bone grafts are still under development; it is not a routine patient treatment.

➤ Compare Therapies

Which Regenerative Therapy Is Right for You?

Comparison of regenerative therapies at IRM Hospital
TherapyWhat it usesHow it is givenCommonly considered for
Stem cell therapyMesenchymal stem cellsInjection into the affected area or IV infusionJoints, cartilage, and some neurological & autoimmune conditions
Exosome therapyCell-derived vesiclesInjection into the affected area or IV infusionHair, skin, joints, anti-ageing
PRP therapyPlatelets from your own bloodInjectionHair, skin, joint pain
Cell-based immunotherapyNK cells / CAR-T cellsIV infusionCertain cancers, case by case
IV therapyVitamins, antioxidants, NAD+IV dripWellness and recovery support
Peptide therapySpecific peptidesAs prescribed by your doctorRecovery, wellness
EBO2Your own blood, ozone & oxygenCircuit outside the body, similar to dialysisSelected patients
Cultured skin & hair cellsFibroblasts, keratinocytes, follicle cellsApplied or injected into the skinSkin, scars, burns, hair
Gene therapyGenesSpecialist protocolSelected conditions

Your specialist will advise which option, if any, suits your condition.

➤ Conditions

What Conditions Can Regenerative Medicine Treat?

Regenerative medicine is used or being studied for more than 100 conditions, including osteoarthritis, tendon and ligament injuries, back pain, autoimmune diseases, neurological conditions such as autism and cerebral palsy, heart and lung disease, diabetes, eye diseases, skin wounds and blood disorders. Some uses are well established; others are still being researched, so suitability depends on each patient’s assessment.

Main groups of conditions treated with regenerative medicine

● Established    ● Growing evidence    ● Under research

Established: standard, approved treatment · Growing evidence: offered by specialist centres, results vary · Under research: being studied in clinical trials

Conditions We Commonly Treat at IRM

Arthritis

Regenerative treatment options for inflammatory and degenerative arthritis.

Osteoarthritis

Wear-and-tear joint disease of the knee, hip and other joints.

Juvenile Arthritis

Arthritis that begins in childhood, assessed by our specialists.

Avascular Necrosis (AVN)

Loss of blood supply to bone, most often in the hip.

Autism Spectrum Disorder

A neurodevelopmental condition; cell therapy is offered alongside speech and behavioural therapies.

Cerebral Palsy

Movement disorders caused by early brain injury; treatment is combined with rehabilitation.

Muscular Dystrophy

Inherited conditions that cause progressive muscle weakness.

Post-COVID Lung Fibrosis

Lung scarring that can follow severe COVID-19.

Complete List of Conditions Treated with Regenerative Medicine

Joints, Bone & Cartilage

● Established

  • Knee cartilage defects (approved chondrocyte cell therapy in Europe)

● Growing evidence

  • Osteoarthritis (knee, hip, shoulder, spine, hand, ankle)
  • Avascular necrosis (hip)
  • Knee and hip joint degeneration
  • Fractures that are not healing
  • Stress fractures
  • Bursitis
  • Outer hip (trochanteric) pain

● Under research

● Growing evidence

  • Degenerative disc disease and disc tears
  • Discogenic low back pain
  • Herniated and bulging discs (neck and back)
  • Spine arthritis
  • Sacroiliac (SI) joint dysfunction
  • Chronic low back pain

● Under research

  • Cervical and lumbar spondylosis
  • Ankylosing spondylitis
  • Sciatica
  • Piriformis syndrome
  • Cervicogenic headache

● Growing evidence

  • Tendinitis and tendinopathy (elbow, shoulder, knee, wrist, ankle)
  • Tendon tears
  • Rotator cuff tears
  • Meniscus tears
  • Labral tears (hip and shoulder)
  • Ligament sprains and tears, including ACL
  • Tennis elbow and golfer’s elbow
  • Plantar fasciitis
  • Achilles tendon injuries
  • Muscle strains and tears
  • Sports injuries

● Under research

  • Faster recovery after orthopaedic surgery (ACL, meniscus, rotator cuff repair)

● Under research

  • Carpal tunnel syndrome
  • Thoracic outlet syndrome
  • Nerve inflammation
  • Post-concussion syndrome

● Established

  • Multiple sclerosis (blood stem cell transplant, in specialist centres)
  • Spinal muscular atrophy (gene therapy, in specialist centres)
  • Leukodystrophies such as adrenoleukodystrophy, metachromatic leukodystrophy and Krabbe disease (specialist centres)
  • AADC deficiency (gene therapy, in specialist centres)

● Under research

● Established

  • Complex anal fistulas in Crohn’s disease (donor cell therapy in Europe)
  • Severe combined immunodeficiency (SCID) and other inherited immune disorders (specialist centres)

● Under research

  • Autoimmune diseases
  • Systemic lupus erythematosus (SLE)
  • Crohn’s disease
  • Ulcerative colitis
  • Alopecia areata

● Under research

  • Peripheral vascular disease
  • Critical limb ischaemia
  • Congestive heart failure
  • Heart attack (myocardial infarction)
  • Dilated cardiomyopathy

● Under research

● Under research

  • Type 1 diabetes
  • Type 2 diabetes
  • Metabolic syndrome
  • Chronic kidney disease
  • Acute kidney injury
  • Diabetic kidney disease (nephropathy)
  • Liver cirrhosis

● Established

  • Dystrophic epidermolysis bullosa (gene therapy, in specialist centres)

● Growing evidence

  • Male pattern hair loss
  • Female hair thinning

● Under research

  • Diabetic foot ulcers
  • Pressure ulcers (bed sores)
  • Venous leg ulcers
  • Chronic non-healing wounds
  • Burns
  • Scars, including acne scars
  • Skin ageing and wrinkles

● Established

  • Retinitis pigmentosa and Leber congenital amaurosis caused by the RPE65 gene (gene therapy)
  • Severe corneal damage, such as chemical burns (limbal stem cell therapy)

● Under research

  • Other forms of retinitis pigmentosa
  • Age-related macular degeneration
  • Diabetic retinopathy
  • Glaucoma
  • Optic nerve atrophy
  • Corneal ulcers
  • Dry eye

● Under research

  • Male infertility (azoospermia, low sperm count)
  • Female infertility (ovarian failure, poor egg quality)
  • Thin or damaged uterine lining (Asherman syndrome)
  • Erectile dysfunction

● Established

  • Leukaemias (ALL, AML, CLL, CML and others)
  • Lymphomas, including Hodgkin and diffuse large B-cell lymphoma
  • Multiple myeloma
  • Myelodysplastic syndrome and myeloproliferative disorders
  • Aplastic anaemia, Fanconi anaemia and other bone marrow failure
  • Sickle cell disease
  • Beta-thalassaemia major
  • Haemophilia A and B (gene therapy)
  • Inherited platelet disorders
  • Certain childhood solid tumours (neuroblastoma, medulloblastoma, retinoblastoma)
  • Advanced melanoma (gene therapy)

● Established

  • Mucopolysaccharidoses (Hurler, Hunter, Sanfilippo, Morquio and others)
  • Selected storage disorders such as Gaucher and Niemann-Pick disease

● Under research

  • Cystic fibrosis

Please note: not every condition listed is treated at IRM Hospital. Some, such as stem cell transplants for blood cancers or gene therapies for rare inherited diseases, are performed only in specialist transplant and cancer centres. Contact our team and we will tell you whether your condition can be assessed at IRM.

➤ Your Journey

Your Regenerative Treatment Journey at IRM

Get in Touch

Call our coordinator on +92 336 4367367 or book online through our appointments page.

Specialist Consultation

We review your symptoms, medical history and previous reports.

Assessment & Tests

Examinations and tests confirm whether treatment is suitable for you.

Personalised Plan

Your options, expected course, possible risks and costs are explained clearly before you decide.

Treatment

Carried out by our team, with cell products prepared and tested in our own lab where needed.

Follow-up & Rehabilitation

Progress reviews and supportive care such as physiotherapy.

➤ Inside Our Lab

Regen Cell Bio: Our In-House Cell & Tissue Laboratory

Established in 2019, Regen Cell Bio prepares the stem cells, exosomes and other cell products used at IRM Hospital. Our processes follow Good Manufacturing Practice (GMP) principles and the quality and safety standards of the EU Tissues and Cells Directive (2004/23/EC).

➤ Meet Your Specialists

The Specialists Behind Your Care

Dr. Syed Salman Naeem Gilani

CEO & Medical Director, IRM Hospital

Dr. Syed Salman Gilani leads regenerative and stem cell care at IRM Hospital, from the first consultation to follow-up.

“Regenerative medicine is about giving the body the right tools to heal. Every plan we make starts with an honest assessment of what can help each patient.”

Dr. Sidra Bokhari

Lab Director (In-charge), Regen Cell Bio Laboratory, IRM Hospital

Dr. Sidra Bokhari leads Regen Cell Bio, where the stem cells, exosomes and other cell products used at IRM are prepared and quality-tested. She medically reviewed this page.

➤ Safety First

Is Regenerative Medicine Safe and Right for Me?

Regenerative treatments are not suitable for everyone. Your specialist considers your diagnosis, overall health, medicines and test results before recommending any therapy.

You May Be a Candidate If You:

Treatment May Not Be Suitable If You Have:

Our commitment: many regenerative therapies are still being studied, and results vary between patients. We explain the evidence honestly, never promise a cure, and encourage you to ask questions. International regulators such as the US FDA also advise patients to ask about evidence and safety before any regenerative treatment.

Not Sure Which Therapy Fits Your Condition?

Talk to our regenerative medicine team. We’ll review your reports and explain your options honestly.

➤ Watch & Learn

Regenerative Medicine Explained

➤ FAQs

Regenerative Medicine FAQs

Regenerative medicine is a branch of medicine that aims to repair or replace damaged cells, tissues and organs using living cells and biological products such as stem cells, exosomes and platelet-rich plasma (PRP).

Yes. IRM Hospital in DHA Phase 2, Islamabad offers stem cell, exosome, PRP, cell-based immunotherapy and other regenerative treatments, supported by its own cell and tissue laboratory, Regen Cell Bio.

Stem cell therapy uses living cells; exosomes are the tiny messenger particles that cells release; PRP uses concentrated platelets from your own blood. Your specialist will advise which suits your condition.

Yes. Stem cells, exosomes and other cell products are prepared and quality-tested at Regen Cell Bio, IRM Hospital’s in-house laboratory, established in 2019.

Most treatments are injections or IV drips. Where a collection step such as bone marrow or fat harvesting is needed, it is done under local anaesthetic. Your care team explains what to expect for your procedure.

It depends on the therapy and the condition. Some patients notice changes over weeks to months, and your specialist explains realistic expectations before treatment.

Every treatment carries some risk. We reduce it through specialist assessment, donor screening and laboratory testing of every cell product, and we explain the evidence and possible side effects before you decide.

Call our coordinator on +92 336 4367367, or book through our appointments page at irmsc.com/appointments.

The information on this page is for general education and does not replace a consultation with a qualified doctor. Regenerative treatments are offered only after a specialist assessment; suitability, possible benefits and risks differ for each patient, and many cell therapies are still being studied in clinical research.